Medical Scientist Training Program

    Past Colloquia - 2006

    Monday, November 6

    Randolph Hasting, M.D., Ph.D., Associate Professor, Dept. of Anesthesiology, UCSD School of Medicine

    Bernard Wood, M.D., Ph.D., D.Sc., Henry R. Luce Professor of Human Origins, Center for the Advanced Study of Hominid Paleobiology, Dept. of Anthropology, George Washington University Adjunct Senior Scientist at the National Museum of Natural History, The Smithsonian Institution

    Biomedical Magazine Review:  Bakre et al. Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor.  Nat Med 2002; 8:995-1003

    Career Perspectives Speaker:  The reconstruction of human evolutionary history through developing and improving the ways we analyze the hominid fossil record; evolution of human growth and development.

    Wednesday, October 25

    Roland Blantz, M.D., Professor & Head, Dept. of Medicine, Div. of Nephrology-Hypertension

    Peter Agre, M.D., Nobel Prize, Chemistry 2003, Vice Chancellor for Science & Technology, Professor of Cell Biology, Duke University Medical Center

    Biomedical Magazine Review:  Habashi JP et al. Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome.   Science 2006; 312:117-121.

    Career Perspectives Speaker:  Molecular and cellular analysis of the transport of water across cell membranes in health and disease; aquaporins.

    Wednesday, September 20

    Ajit Varki, M.D., Distinguished Professor of Medicine and Cellular & Molecular Medicine, Associate Dean for Physician-Scientist Training

    Judith Swain, M.D., Founding Dean for Translational Research and Professor of Medicine

    Edward Holmes, M.D., Vice-Chancellor for Health Sciences, Dean, UCSD School of Medicine, Exe. Dpty. Chairman-Elect, Clinical Translational Sciences, Biomedical Research Council and Lien Ying Chow Professor of Medicine, Yong Loo Lin School of Medicine, National University of Singapore

    Biomedical Magazine Review:  "Cytokine Storm in a Phase 1 Trial of the Anti-CD28 Monoclonal Antibody TGN1412," Suntharalingam et al. NEJM 2006:355

    Career Perspectives Speaker:  Genetic basis of cardiovascular development and disease.  Role of growth factors in angiogenesis.  Research program development and interdisciplinary collaboration across the continuum of discovery, development and patient care.

    Closing Comments

    Monday, August 21

    Maripat Corr, M.D., Associate Professor of Medicine, Div. of Rheumatology

    Patricia Thistlethwaite, M.D., Ph.D., Associate Professor of Surgery, Div. of Cardiovascular & Thoracic Surgery

    Nissi Varki, M.D., Professor of Pathology & Medicine Cancer Biology Program

    Women in Medicine

    Monday, July 31

    Christine Moutier, M.D., Asst. Clinical Professor, Dept. of Psychiatry, Asst. Dean, Students & Curricular Affairs

    Robert Hertzka, M.D., President, California Medical Association (CMA), Professor, Dept. of Anesthesiology

    Bryan Liang, JD, M.D., Ph.D., Professor of Law, California Western School of Law, Exec. Dir., Institute of Health Law Studies

    Sanjay Nigam, M.D., Professor of Pediatrics, Medicine, and Cellular & Molecular Medicine, Author, The Snake Charmer and The Transplanted Man

    Alternatives to the Scientist Pathway

    Career Perspectives of a Physician-Scientist-Writer

    Monday, May 22

    Douglas Richman, M.D., Professor of Pathology & Medicine, F.S. Riford Chair in AIDS Research, Dir., UCSD Center for AIDS Research

    Helen Ranney, M.D., Professor and Chair Emeritus, Dept. of Medicine

    Biomedical Magazine Review:  Mattapallil JJ et al.  Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection. Nature 2005; 434:1080-1.

    Career Perspectives Speaker:  Structure and function of hemoglobin, hemoglobinopathies, biochemistry and genetics underlying sickle cell anemia

    Monday, April 24

    Ravindra Mehta, MBBS, M.D., Professor of Medicine, Div. of Nephrology and Hypertension, Assoc. Chair for Clinical Affairs

    Chuck Stevens, M.D., Ph.D., Professor and Vincent J. Coates Chair, Molecular Neurobiology, Salk

    Biomedical Magazine Review:  Mishra J et al.  Neutrophil gelatinase-Assoc.d lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 2005; 365:1231-8.

    Career Perspectives Speaker:  Mechanisms responsible for neuronal synaptic transmission. Function of hippocampal synapses; mechanisms of synaptic plasticity and the relevance of plasticity to neuronal computations.  Molecular basis of neurotransmitter release.

    Monday, March 27

    Anthony Wynshaw-Boris, M.D., Ph.D., Professor of Pediatrics & Medicine, Dir., UCSD Center for Human Genetics & Genomics

    Shu Chien, M.D., Ph.D., Professor of Bioengineering & Medicine, Dir., Whitaker Inst. of Biomedical Engineering

    Biomedical Magazine Review:  Iafrate et al. "Detection of large scale variation in the human genome." Nat Genet. 2004; 36:949-51.

    Career Perspectives Speaker:  Effects of mechanical forces on gene expression and signal transduction.  Role of biomechanical factors in atherosclerosis. Molecular, cellular, and tissue bioengineering.

    Tuesday, February 28

    Gary Firestein, M.D., Professor of Medicine, Chief, Div. of Rheumatology, Allergy & Immunology, Exec. Dir., UCSD Center for Innovative Therapy

    Sydney Brenner, M.D., Distinguished Professor, Salk Institute for Biological Studies, Nobel Laureate in Medicine 2002

    Biomedical Magazine Review:  Camps et al. "Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis." Nat Med. 2005; 11:936-43.

    Career Perspectives Speaker:  Genetics and molecular biology; discovery of the existence of mRNA and demonstration of how amino acid order is established in proteins; pioneering work with the roundworm C. elegans as a model of nerve cell function, aging and apoptosis.

    Monday, January 23

    Sanford Shattil, M.D., Professor of Medicine, Editor-in-Chief, Blood

    Pedro Cuatrecasas, M.D., Adjunct Professor of Pharmacology & Medicine, President, Retired, Parke Davis/Warner Lambert Pharmaceutical Research Div.

    Special Presentation:  "An Editor's Perspective:  How to Write a Paper for a Scientific Journal in 2006"

    Career Perspectives Speaker:  Affinity chromatography, membrane  receptors, signal transduction for insulin and other growth factors; Discovery and development of drugs for diabetes, HIV, bacterial infections, epilepsy, cancer, Alzheimer's and depression.